Genome-wide approaches to monitor pre-mrna splicing
Pre-mRNA processing is an essential control-point in the gene expression pathway of eukaryotic organisms. The budding yeast Saccharomyces cerevisiae offers a powerful opportunity to examine the regulation of this pathway. In this chapter, we will describe methods that have been developed in our lab and others to examine pre-mRNA splicing from a genome-wide perspective in yeast. Our goal is to provide all of the necessary information-from microarray design to experimental setup to data analysis-to facilitate the widespread use of this technology. © 2010 Elsevier Inc. All rights reserved.
Methods in Enzymology
Inada, Maki and Pleiss, Jeffrey A., "Genome-wide approaches to monitor pre-mrna splicing" (2010). Faculty Articles Indexed in Scopus. 1517.