Rapid self-assembly of core-shell organosilicon microcapsules within a microfluidic device
The preparation of hierarchically structured organosilicon microcapsules from commercially available starting materials is described. Using a microfluidic device, an emulsion of dichlorodiphenylsilane is formed in a continuous phase of aqueous glycerol. The silane droplets undergo hydrolysis, condensation, and crystallization within minutes to form self-assembled, core-shell microcapsules. The microparticles have been characterized with light and electron microscopy, nuclear magnetic resonance spectroscopy (NMR), diffusion-ordered NMR spectroscopy (DOSY), Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), and powder X-ray diffraction (XRD). The characterization data show that the microcapsule walls consist of amorphous, oligomeric poly(diphenylsiloxane) surrounded by a spiny layer of crystalline diphenylsilanediol. Glycerol is occluded within the wall material but is not covalently bound to the silicon components. Glycerol is a crucial element for producing low-dispersity microcapsules with well-ordered surface spines, as the use of methyl cellulose as viscomodifier yields amorphous surfaces. © 2006 American Chemical Society.
Journal of the American Chemical Society
Steinbacher, Jeremy L.; Moy, Rebecca W.Y.; Price, Kristin E.; Cummings, Meredith A.; Roychowdhury, Chandrani; Buffy, Jarrod J.; Olbricht, William L.; Haaf, Michael; and McQuade, D. Tyler, "Rapid self-assembly of core-shell organosilicon microcapsules within a microfluidic device" (2006). Faculty Articles Indexed in Scopus. 1851.