The effects of terminating and detraining on enzyme activities of heart and skeletal muscle of trained rats

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Thirty-six male Sprague-Dawley rats with an average beginning weight of 360 grams were trained for 5 weeks with an exercise program consisting of swimming for 35 minutes a day in water at 35 ° C. At the end of this training period one of the trained groups terminated the exercise program, while the remaining experimental group of animals detrained by swimming a minute less each day for 5 weeks following the training. Control-fed non-swimming animals served as controls. The group of animals that terminated the training program gained weight at a rate which was about 60% greater than the controls. The detrained group of animals had adrenals that were significantly heavier (P < 0.05) than the controls while their kidney weights were significantly lighter (P < 0.05). Aldolase, cytochrome oxidase and succinate-cytochrome c reductase activities were determined for both the heart ventricles and gastrocnemii. The results were expressed in terms of unit and total activities. The termination of training significantly changed the succinate-cytochrome c reductase activities of the skeletal muscle (P < 0.05), while the cytochrome oxidase activities and the unit activity of succinate-cytochrome c reductase of the heart ventricles were significantly altered (P < 0.05) for the detrained group. Aldolase revealed no significant enzymatic changes in either heart or skeletal muscle for either of the experimental groups. © 1965 Springer-Verlag.

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Internationale Zeitschrift für Angewandte Physiologie Einschließlich Arbeitsphysiologie

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