Title

Catalysis of the disproportionation of superoxide by metalloporphyrins

Document Type

Article

Publication Date

1-1-1979

Abstract

The efficiencies of several metalloporphyrin complexes at catalyzing the disproportionation of superoxide have been determined at pH 10 in both carbonate and borate buffer systems. Catalytic rate constants were obtained for the iron(III) and cobalt(III) derivatives of tetrakis(4-N-methylpyridyl) porphine, for tetraphenylporphinesulfonatoferrate(III) and for hemin. In addition, the effects of added bovine serum albumin and imidazole were studied. The order of catalytic efficiency is FeTMpyP ≫ FeTMpyP(Im) ≫ FeTPPS(Im) ≈ FeTPPS ≈ FeTPPS·BSA ≈ Fe(EDTA) ≳ CoTMpyP ≫ hemin(Im) ≳ hemin. © 1979. 2 2 2

Publication Name

Journal of Inorganic Biochemistry

Volume Number

11

First Page

261

Last Page

267

Issue Number

3

DOI

10.1016/S0162-0134(00)80022-7

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