Title

Evaluation of the effects of a clinically implemented exercise program on physical fitness, fatigue, and depression in cancer survivors

Document Type

Article

Publication Date

6-1-2018

Abstract

Purpose: Despite national recommendations, exercise programs are still not clinically implemented as standard of care for cancer survivors. This investigation examined the effects of a clinically implemented and personalized exercise program on physical fitness, fatigue, and depression in a diverse population of cancer survivors. The association of various participant characteristics on program performance was also examined. Methods: Data were collected from 170 cancer survivors who had participated in a clinical exercise program. Any cancer type was included and survivors were either undergoing medical treatment or had completed treatment (< 6 months prior to program initiation). Baseline and post program measures of estimated VO peak, grip strength, fatigue, and depression were compared in survivors who completed the program follow-up. Multiple regressions were performed to investigate the association of age, gender, body mass index (BMI), and medical treatment status on baseline and change scores in outcome measures, as well as program adherence. Results: All measures improved in participants who completed the program (p < 0.01). Age, gender, and BMI were associated with baseline measures of estimated VO peak and grip strength (p < 0.01), and age was inversely associated with baseline fatigue (p = 0.02). Only BMI was inversely associated with change in estimated VO peak (p < 0.01). No participant characteristics or baseline measures were predictive of program adherence (p > 0.05). Conclusion: This investigation provides evidence that a personalized, clinical exercise program can be effective at improving physical fitness, fatigue, and depression in a diverse population of cancer survivors. 2 2 2

Publication Name

Supportive Care in Cancer

Volume Number

26

First Page

1861

Last Page

1869

Issue Number

6

DOI

10.1007/s00520-017-4019-7

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